LIPOSOME VARYING INNER MATERIAL COMPOSITION RESPONDING TO EXTERNAL ENVIRONMENT,申请号JP20110076737-传众专利搜索

LIPOSOME VARYING INNER MATERIAL COMPOSITION RESPONDING TO EXTERNAL ENVIRONMENT

申请公布号：JP2012210172(A)

申请号：JP20110076737

申请日期：2011.03.30

申请公布日期：2012.11.01

申请人：

JAPAN SCIENCE & TECHNOLOGY AGENCY

发明人：YOMO TETSUYA;ICHIHASHI IKIKAZU;KOBORI SHUNGO

分类号：C12N15/09;C12M1/00

主分类号：C12N15/09

摘要：<P>PROBLEM TO BE SOLVED: To provide a liposome varying inner material composition responding to an external environment. <P>SOLUTION: There is provided a unilamellar liposome comprising: (a) a DNA comprising a promoter sequence, a riboswitch sequence, a translational initiator sequence, and a polypeptide-encoding sequence; (b) an RNA polymerase; (c) a ribonucleotide; and (d) an acellular protein synthesis system. A biosensor inducing expression of a reporter gene responding to a substance from an external world, a liposome which emits light by recognizing toxic substances in the environment, and a pharmaceutical expressing active components responding to the environment in vivo can be provided by using the invention. <P>COPYRIGHT: (C)2013,JPO&INPIT