CANCER SPECIFIC ANTIBODY AND CELL SURFACE PROTEINS,申请号US201113297783-传众专利搜索

CANCER SPECIFIC ANTIBODY AND CELL SURFACE PROTEINS

申请公布号：US2012128723(A1)

申请号：US201113297783

申请日期：2011.11.16

申请公布日期：2012.05.24

申请人：

CHAHAL FRANCINA C.;ENTWISTLE JOYCELYN;CIZEAU JEANNICK;GLOVER NICHOLAS RONALD;MACDONALD GLEN CHRISTOPHER;VIVENTIA BIOTECHNOLOGIES INC.

发明人：CHAHAL FRANCINA C.;ENTWISTLE JOYCELYN;CIZEAU JEANNICK;GLOVER NICHOLAS RONALD;MACDONALD GLEN CHRISTOPHER

分类号：A61K31/7088;A61P35/00;A61P37/04;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12N15/63

主分类号：A61K31/7088

摘要：The present invention provides the amino acid and nucleic acid sequences of heavy chain and light chain complementarity determining regions of a cancer specific antibody. In addition, the invention provides cancer specific antibodies and immunoconjugates comprising the cancer specific antibody attached to a toxin or label, and methods and uses thereof. The invention also relates to diagnostic methods and kits using the cancer specific antibodies of the invention. Further, the invention provides a novel cancer-associated antigen and its uses thereof.