多肽和含有革兰氏阳性多肽的免疫组合物及使用方法
申请公布号:CN102448489A
申请号:CN201080023599.0
申请日期:2010.03.23
申请公布日期:2012.05.09
发明人:L·L·赫伦-奥尔森;D·M·凯特伦
分类号:A61K39/085(2006.01)I;A61K39/38(2006.01)I;C07K14/00(2006.01)I
主分类号:A61K39/085(2006.01)I
代理人:李进;郭文洁
地址:美国明尼苏达州
摘要:本发明提供可自葡萄球菌属分离的分离多肽。本发明亦提供包含一种或多种所述多肽的组合物、用于制备所述多肽的方法及用于使用所述多肽的方法。
主权项:一种组合物,其包含:与SEQ ID NO:397的氨基酸序列具有至少92%序列相似性的分离多肽,条件是若所述分离多肽在氨基末端包括一个或多个另外的氨基酸,则与SEQ ID NO:399的1‑26位氨基酸相比,所述一个或多个另外的氨基酸包括至少一种氨基酸缺失或至少一种氨基酸取代。
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