PLATELET-DERIVED MICROPARTICLES AS A NOVEL DIAGNOSIS MAKER FOR A CARDIOVASCULAR DISEASE,申请号EP20050708556-传众专利搜索

PLATELET-DERIVED MICROPARTICLES AS A NOVEL DIAGNOSIS MAKER FOR A CARDIOVASCULAR DISEASE

申请公布号：EP1851541(B1)

申请号：EP20050708556

申请日期：2005.02.21

申请公布日期：2011.05.11

申请人：

SAGA UNIVERSITY

发明人：NODE, KOICHI;INOUE, TERUO

分类号：G01N33/50;A61B5/00

主分类号：G01N33/50

摘要：<p>The present invention is directed to a method for evaluating whether coronary artery disease has progressed in a patient previously diagnosed as having the disease, wherein the method includes: (a) obtaining a biological sample from the patient at a first time point and a second time point; (b) detecting the level of platelet-derived microparticles (PDMPs) or a fragment thereof, in the first time point sample and the second time point sample with an antibody to PDMPs or a fragment thereof; wherein an increase in a level of the PDMPs in the second time point sample in comparison to a level in the first time point sample is indicative of progression of coronary artery disease.</p>