DISORDERS OF VASOREGULATION AND METHODS OF DIAGNOSING THEM,申请号EP20080841368-传众专利搜索

DISORDERS OF VASOREGULATION AND METHODS OF DIAGNOSING THEM

申请公布号：EP2215256(A1)

申请号：EP20080841368

申请日期：2008.10.22

申请公布日期：2010.08.11

申请人：

DEWALD, GEORG

发明人：DEWALD, GEORG

分类号：C12Q1/68

主分类号：C12Q1/68

摘要：The present invention relates to various in vitro methods of diagnosing a vasoregulation disorder or a predisposition thereto in a subject being suspected of having developed or of having a predisposition to develop a vasoregulation disorder or in a subject being suspected of being a carrier for a vasoregulation disorder, wherein the vasoregulation disorder is selected from hypertension, migraine, pre-eclampsia and recurrent pregnancy loss. Moreover, the present invention also relates to methods for identifying compounds capable of modulating coagulation factor XII activity, suitable as medicaments or as lead compound for a medicament for the treatment and/or prevention of a vasoregulation disorder. Furthermore, the present invention relates to gene therapy methods and to a kit for diagnosing a vasoregulation disorder.