COMBINATIONS OF MEK INHIBITORS AND RAF KINASE INHIBITORS AND USES THEREOF,申请号CA20082694646-传众专利搜索

COMBINATIONS OF MEK INHIBITORS AND RAF KINASE INHIBITORS AND USES THEREOF

申请公布号：CA2694646(A1)

申请号：CA20082694646

申请日期：2008.07.28

申请公布日期：2009.02.05

申请人：

ARDEA BIOSCIENCES, INC.

发明人：MINER, JEFFREY N.;CHAPMAN, MARK S.;QUART, BARRY;ADJEI, ALEX;YU, CHUNRONG

分类号：A61K39/395

主分类号：A61K39/395

摘要：This invention concerns combinations of inhibitors of MEK, Raf protein kinases, and other kinases includin VEGFRl -3 and PDGFR-ß.. This invention also concerns pharmaceutical compositions comprising the compounds described herein and methods of use of the compounds and compositions described herein, including the use in the treatment and/or prevention of cancer and other hyperproliferative disorders.