Cytotoxicity mediation of cells evidencing surface expression of CD63,申请号US20060362452-传众专利搜索

Cytotoxicity mediation of cells evidencing surface expression of CD63

申请公布号：US7442777(B2)

申请号：US20060362452

申请日期：2006.02.24

申请公布日期：2008.10.28

申请人：

ARIUS RESEARCH INC.

发明人：YOUNG DAVID S. F.;FINDLAY HELEN P.;HAHN SUSAN E.;DA CRUZ LUIS A. G.;SAYEGH DAAD;ROGERS KRISTIAN;KUMAR SHANKAR;HINTON PAUL

分类号：C07K16/00;C07K17/00

主分类号：C07K16/00

摘要：This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMAB of the instant invention.