Cellular physiology workstations for automated data acquisition and perfusion control,申请号US20070824829-传众专利搜索

Cellular physiology workstations for automated data acquisition and perfusion control

申请公布号：US2008227187(A1)

申请号：US20070824829

申请日期：2007.07.03

申请公布日期：2008.09.18

发明人：FARB DAVID H.;GIBBS TERRELL T.;YAGHOUBI NADER

分类号：C12M1/34;C12M1/36;C12M3/00;G01N33/487;G01N33/50

主分类号：C12M1/34

摘要：Cellular physiology workstations for automated data acquisition and perfusion control are described. The cellular physiology workstation may be used for physiological and electrophysiological experiments. Methods for employing such cellular physiology workstations in physiological and electrophysiological experiments are also disclosed. The cellular physiology workstations comprise one or more recording chambers each for holding one or more cells to be measured. One or more cells are place in each recording chamber. Perfusions means, such as an automatic perfusion system is connected to the recording chamber to perfuse the cells with a plurality of solutions containing different concentration of one or more agents to be tested. Biosensors, such as patch clamps, electrodes, or microscopes are positioned to detect a response from the cell. The cellular physiology workstation may optionally comprise injecting means for introducing an injection solution into the cell before and during analysis.