CD127 EXPRESSION INVERSELY CORRELATES WITH FOXP3 AND SUPPRESSIVE FUNCTION OF CD4+ TREGS,申请号CA20072655392-传众专利搜索

CD127 EXPRESSION INVERSELY CORRELATES WITH FOXP3 AND SUPPRESSIVE FUNCTION OF CD4+ TREGS

申请公布号：CA2655392(A1)

申请号：CA20072655392

申请日期：2007.05.31

申请公布日期：2007.12.06

申请人：

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人：PUTNAM, AMY;BLUESTONE, JEFFREY A.;LIU, WEIHONG

分类号：A61K35/14;A61P37/06;C12N5/0783;C12Q1/02;C12Q1/04;G01N33/567

主分类号：A61K35/14

摘要：<p>The invention provides methods of isolating CD127lo/- immunosuppressive r egulatory T cells which can be greatly enriched for FoxP3, methods of expand ing the isolated cells, pharmaceutical compositions of such cells, and metho ds of their use in the treatment of autoimmune and other immune system media ted disorders.</p>