MEDICINE CONTAINING TELOMERASE-INHIBITING ENA OLIGONUCLEOTIDE,申请号JP20060315060-传众专利搜索

MEDICINE CONTAINING TELOMERASE-INHIBITING ENA OLIGONUCLEOTIDE

申请公布号：JP2007169269(A)

申请号：JP20060315060

申请日期：2006.11.22

申请公布日期：2007.07.05

申请人：

SANKYO CO LTD

发明人：KOIZUMI MAKOTO;ANDO OSAMU

分类号：A61K31/7088;A61K48/00;A61P35/00;A61P43/00;C07H21/04

主分类号：A61K31/7088

摘要：PROBLEM TO BE SOLVED: To provide a new ENA antisense compound inhibiting the action of a telomerase and effective for the treatment of a disease associated with the telomerase. SOLUTION: The medicine contains a compound represented by general formula: E1-B1-B2-B3-B4-E2 (I) (wherein, E1 is a group represented by formula: R1-, or the like; E2 is a group represented by formula: -B7-R2, or the like; B4, B5 and B8 are the same or different, and each T<SP>p</SP>or the like; B1, B2, B3 and B12 are the same or different, and each G<SP>p</SP>or the like; B16 is C<SP>p</SP>or the like; B6, B10, B14 and B18 are the same or different and each A<SP>p</SP>or the like), or a pharmacologically acceptable salt thereof as an active ingredient. COPYRIGHT: (C)2007,JPO&INPIT