VACCINE COMPRISING A MONOCLONAL ANTIBODY BINDING DENDRITIC CELLS CONJUGATED TO A HUMAN CHORIONIC GONADOTROPIN

申请公布号：EP1789093(A2)

申请号：EP20050856893

申请日期：2005.07.28

申请公布日期：2007.05.30

申请人：

CELLDEX THERAPEUTICS, INC.

发明人：KELER, TIBOR;ENDRES, MICHAEL;HE, LIZHEN;RAMAKRISHNA, VENKY

分类号：A61K47/48;A61K39/00;A61K39/395;A61P37/04;C07K14/59;C07K16/28

主分类号：A61K47/48

摘要：The present invention provides novel antibody vaccine conjugates and methods of using the same to induce a cytotoxic T cell (CTL) response. In a particular, embodiment, the vaccine conjugate includes a human chorionic gonadotropin beta subunit (betahCG) antigen linked to an anti-mannose receptor (MR) antibody.

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