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BINDING MOLECULES CAPABLE OF NEUTRALIZING RABIES VIRUS AND USES THEREOF

申请公布号:EP1749029(A2)

申请号:EP20050747901

申请日期:2005.05.26

申请公布日期:2007.02.07

申请人:
CRUCELL HOLLAND B.V.

发明人:BAKKER, ALEXANDER, BERTHOLD, HENDRIK;MARISSEN, WILLEM EGBERT;KRAMER, ROBERT ARJEN;DE KRUIF, CORNELIS ADRIAAN

分类号:C07K16/10;A61K39/395;A61P31/14;C12N5/10;C12N15/13;C12N15/63;G01N33/569

主分类号:C07K16/10

摘要:<p>The present invention provides binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. The invention further provides nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. Preferably, they can be used in the postexposure prophylaxis of rabies.</p>

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