CRYSTAL POLYMORPH OF HYDROXYNOREPHEDRIN DERIVATIVE HYDROCHLORIDE

申请公布号：WO2006123517(A1)

申请号：WO2006JP308592

申请日期：2006.04.24

申请公布日期：2006.11.23

申请人：

KISSEI PHARMACEUTICAL CO., LTD.;KASAI, KIYOSHI;TODA, MICHIO

发明人：KASAI, KIYOSHI;TODA, MICHIO

分类号：C07C217/54;A61K31/216;A61P13/02

主分类号：C07C217/54

摘要：<p>There is provided a novel crystal polymorph of ethyl (-)-2-[4-[2-[[1S,2R]-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-2,5-dimethylphenoxyacetate hydrochloride which can be identified by characteristic diffraction peaks of powder X-ray diffractometry, etc., through specified process from ethyl (-)-2-[4-[2-[[1S,2R]-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-2,5-dimethylphenoxyacetate hydrochloride.</p>

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