Molecular resonant tunneling sensor and methods of fabricating and using the same
申请公布号:EP1712891(A2)
申请号:EP20050020589
申请日期:2005.09.21
申请公布日期:2006.10.18
发明人:BARTH, PHILLIP W.;MYERHOLTZ, CARL A.
分类号:G01N15/10;C12Q1/68;G01N27/416
主分类号:G01N15/10
摘要:<p>Resonant tunneling devices and methods of using and fabricating the same are provided. The subject devices include a first 110 and second 111 fluid containment members separated by a fluid barrier 109 having a single nanopore 101 therein providing fluid communication between the first and second fluid containment members, wherein the nanopore 101 has a top inner diameter that is smaller than a bottom inner diameter and includes first 107 and second 105 perimeter electrodes separated by an insulator element 106, and a proteinaceous channel 102 positioned in the nanopore. Also provided are methods of fabricating such a device and methods of using such a device for improved detection and characterization of a sample.</p>
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