Antibacterial salts of n4,n4'-decamethylene bis - aminiquinaldine

申请公布号：NL6915576(A)

申请号：NL19690015576

申请日期：1969.10.15

申请公布日期：1971.04.19

分类号：C07D215/46;(IPC1-7):61K27/00;01N9/22;07D33/54

主分类号：C07D215/46

摘要：<p>Antibacterial salts of N4,N4'-decamethylene bis aminiquinaldine. M3A. Of formula (I):- Specifically claimed are the diacetate, dilactate, tartrate, diundecylate, disalicylate and dibenzoate. Used as antibacterial and antifungal agents. Solubilities and consequent activity in practice vary. The diacetate is soluble at 1% in water, the dilacetate at 10% and the 1 (+) tartrate at 1%. Useful in tablets, ointments and creams. The undecylenate is alcohol-soluble and may be used in sprays. The minimum inhibitory concentrations of the diacetate against various organisms are:- staph. aureus 1/256,000, Strep. haemolyticus (Gp.A) 1/256,000, Enterococcus 1/120,000, candida sp. 1/32,000, Trichophyton mentagrophytes 1/10,000.</p>

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