METHODS FOR PREDICTING PREGNANCY OUTCOME IN A SUBJECT BY hCG ASSAY,申请号EP20000935949-传众专利搜索

METHODS FOR PREDICTING PREGNANCY OUTCOME IN A SUBJECT BY hCG ASSAY

申请公布号：EP1183390(B8)

申请号：EP20000935949

申请日期：2000.05.12

申请公布日期：2006.05.03

申请人：

THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

发明人：O'CONNOR, JOHN;BIRKEN, STEVEN;KOVALEVSKAYA, GALINA

分类号：C12Q1/68;G01N33/53;B01J13/00;B05D1/18;C07H21/02;C07H21/04;C07K16/26;C12N15/00;C12N15/02;C12Q1/70;G01N21/64;G01N33/00;G01N33/531;G01N33/533;G01N33/543;G01N33/577;G01N33/76

主分类号：C12Q1/68

摘要：<p>The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.</p>