METHOD FOR OBTAINING SUTURING MATERIAL OUT OF BIOLOGICAL RAW MATERIAL,申请号RU20030116925-传众专利搜索

METHOD FOR OBTAINING SUTURING MATERIAL OUT OF BIOLOGICAL RAW MATERIAL

申请公布号：RU2252027(C2)

申请号：RU20030116925

申请日期：2003.06.09

申请公布日期：2005.05.20

发明人：OSAULENKO VLADIMIR MIKHAJLOVICH

分类号：A61K35/12;A61L17/08

主分类号：A61K35/12

摘要：FIELD: medicine. ^ SUBSTANCE: the method deals with selecting primary raw material, followed by acidic-alkaline treatment, cutting, forming semi-finished ligatures, followed by drying, polishing and packing into ampoules or parcels, followed by sealing and sterilization. As primary raw material one should predominantly apply porcine viscera followed by elution of ballast substances with1.3 dimethylketone, treatment with succinic anhydride, then comes cutting for, at least, 2-4 parts to be sterilized in dry water-free state at no any preliminary conservation with predominantly radiation emission followed by material rehydration and packing into individual parcels, then comes conservation and sealing individual packing with sterile ligatures. Rehydration of ligatures should be performed, for example, for 16 h in 0.02% solution of (1.2-ethylene-bis N diethylcarbodecynoxymethyl) ammonium chloride. Power of radiation emission at sterilization corresponds to at least 15 kGy, as for polishing, it is predominantly fulfilled due to "drilling". Simultaneously one should perform group sterilization of ligatures without individual packing followed by packing the sterile material. Group sterilization of suture material should be performed without individual packing with gas method of ethylenoxide, the mixture of ethylenoxide with methyl bromide or beta-propiolactone followed by packing the sterile material. The method provides considerable decrease of production cost price, decreased expenses of primary raw material, improved histocompatibility, decreased allergic and purulent-inflammatory complications and keeping strong parameters during sterilization. ^ EFFECT: higher efficiency. ^ 5 cl, 3 ex, 1 tbl