Novel G-protein coupled receptor (GPCR) variants and methods of use thereof
申请公布号:US2004253668(A1)
申请号:US20030349528
申请日期:2003.01.22
申请公布日期:2004.12.16
发明人:RAMANATHAN CHANDRA S.;GOPAL SHUBA;MINTIER GABRIEL;FEDER JOHN N.
分类号:C07K14/705;C12N15/12;(IPC1-7):C12P21/02;C07H21/04
主分类号:C07K14/705
摘要:The present invention describes human G-protein coupled receptors (GPCRs) and their encoding polynucleotides. Also described are expression vectors, host cells, antisense molecules, and antibodies associated with the GPCR polynucleotides and/or polypeptides of this invention. In addition, methods for treating, diagnosing, preventing, and screening for disorders or diseases associated with abnormal biological activity of GPCR are described, as are methods for screening for modulators, e.g., agonists or antagonists, of GPCR activity and/or function.