Melanin concentrating hormone receptor ligands

申请公布号：US2004229883(A1)

申请号：US20040820344

申请日期：2004.04.08

申请公布日期：2004.11.18

申请人：

BAKTHAVATCHALAM RAJAGOPAL;THURKAUF ANDREW;HUTCHISON ALAN

发明人：BAKTHAVATCHALAM RAJAGOPAL;THURKAUF ANDREW;HUTCHISON ALAN

分类号：G01N33/53;A61K31/451;A61K31/495;A61P3/04;A61P3/10;A61P9/10;A61P15/00;A61P15/10;A61P25/18;C07D211/14;C07D295/08;C07D295/096;G01N33/566;(IPC1-7):A61K31/495;C07D241/04

主分类号：G01N33/53

摘要：Disclosed are compounds of the formula: and the pharmaceutically acceptable salts thereof wherein Q, X, Y, Z, and R1 R9, and R12-R19 are defined herein. These compounds are selective modulators of MCH 1 receptors that are, therefore, useful in the treatment of a variety of metabolic, feeding, and sexual disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also disclosed.

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