Hemostatic wound dressings and methods of making same,申请号EP20030254107-传众专利搜索

Hemostatic wound dressings and methods of making same

申请公布号：EP1462123(A1)

申请号：EP20030254107

申请日期：2003.06.27

申请公布日期：2004.09.29

申请人：

ETHICON, INC.

发明人：LOONEY, DWAYNE LEE;CRILLEY, JOHN;GUO, JIAN XIN;ZHANG, GUANGHUI;PENDHARKAR, SANYOG MANOHAR

分类号：A61F13/00;A61L15/28;A61L15/42;(IPC1-7):A61L15/28;A61L15/32;A61L15/44;A61L15/64

主分类号：A61F13/00

摘要：The present invention is directed to methods of making wound dressings that include the steps of providing a solution of a water-soluble or water-swellable biocompatible polymer dissolved in a solvent for the polymer, providing a fabric substrate having a first surface and a second surface opposing the first surface, the fabric having properties effective for use as a hemostat and containing fibers prepared from a biocompatible polymer, contacting the fabric substrate with the polymer solution under conditions effective to distribute the polymer solution substantially homogenously on the first and second surfaces and through the fabric substrate, transferring the fabric substrate having the polymer solution substantially homogenously distributed there through to a lyophilization unit under conditions effective to maintain the homogeneous distribution on and throughout the substrate, and lyophilizing the fabric having the polymer solution distributed there through, thereby providing a porous, polymeric matrix substantially homogeneously distributed on the first and second surfaces and through the fabric, the matrix being made-up of the lyophilized water-soluble or water-swellable polymer.