ANTISENSE MODULATION OF PTP1B EXPRESSION

申请公布号：IL158778(D0)

申请号：IL20020158778

申请日期：2002.05.13

申请公布日期：2004.05.12

申请人：

ISIS PHARMACEUTICALS, INC.

分类号：C12N15/09;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P3/04;A61P3/10;A61P35/00;C12N15/113;(IPC1-7):C07H

主分类号：C12N15/09

摘要：<p>Compounds, compositions and methods are provided for modulating the expression of PTP1B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTP1B. Methods of using these compounds for modulation of PTP1B expression and for treatment of diseases associated with expression of PTP1B are provided.</p>

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