DIBENZOSBERANYL PIPERAZINE DERIVATIVES AND DRUG-RESISTANCE OVERCOMING AGENTS CONTAINING THE DERIVATIVES
申请公布号:EP1336608(A1)
申请号:EP20010982865
申请日期:2001.11.20
申请公布日期:2003.08.20
发明人:TAKEUCHI, TSUTOMU;TAKAYANAGI, HIROAKI;KOBAYASHI, SEIKI;OSA, YUMIKO;SUZUKI, YUMIKO;SATO, YOKO;SAKAGUCHI, M;MIYATA, Y
分类号:C07D295/088;A61K31/495;A61P33/06;A61P43/00;C07D241/04;C07D295/084;(IPC1-7):C07D295/088
主分类号:C07D295/088
摘要:<p>Dibenzosuberanyl piperazine derivatives represented by the following formula (I): <CHEM> wherein R represents an aliphatic hydrocarbon group, which may contain one or more heteroatom-containing substituent groups and may preferably contain 2 to 30 carbon atoms, and physiologically acceptable salts thereof; and medicinal compositions containing these dibenzosuberanyl piperazine derivatives and/or physiologically acceptable salts thereof. These compounds show effectiveness in allowing resistance-acquired causes of diseases to restore sensitivity to drug, that is, a resistance overcoming effect.</p>
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