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1,25-二羟基-16,22,23-三烯-胆钙化醇衍生物

申请公布号:CN1110477C

申请号:CN97103358.7

申请日期:1997.03.20

申请公布日期:2003.06.04

申请人:
弗·哈夫曼-拉罗切有限公司

发明人:B·M·赫尼思;J·A·拉克比利;M·R·尤斯库科维克

分类号:C07C401/00;C07F7/18;A61K31/59;A61P17/00;A61P35/02;A61P17/06

主分类号:C07C401/00

代理机构:
北京市中咨律师事务所

代理人:黄革生;刘金辉

地址:瑞士巴塞尔

摘要:本发明涉及一种具有下列通式的化合物其中R是羟基,R<SUP>1</SUP>是H<SUB>2</SUB>或CH<SUB>2</SUB>,或者R是氢或氟,R<SUP>1</SUP>是CH<SUB>2</SUB>。式I的化合物可用作治疗过度增生的皮肤病如牛皮癣,肿瘤疾病如白血病,和皮质腺疾病如粉刺和皮炎的药剂。∴

主权项:1.一种具有下列通式的化合物<img file="C9710335800021.GIF" wi="768" he="564" />其中R是羟基,R<sup>1</sup>是H或CH<sub>2</sub>,或者R是氢或氟,R<sup>1</sup>是CH<sub>2</sub>。

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