METHOD OF PRODUCING GALACTO TYPE TREHALOSE OR DERIVATIVE THEREOF AND LIGAND FOR VERO TOXIN ORIGINATING FROM TREHALOSE OBTAINED USING THE SAME,申请号JP20010265737-传众专利搜索

METHOD OF PRODUCING GALACTO TYPE TREHALOSE OR DERIVATIVE THEREOF AND LIGAND FOR VERO TOXIN ORIGINATING FROM TREHALOSE OBTAINED USING THE SAME

申请公布号：JP2003073391(A)

申请号：JP20010265737

申请日期：2001.09.03

申请公布日期：2003.03.12

申请人：

NAGOYA INDUSTRIAL SCIENCE RESEARCH INST

发明人：NISHIDA YOSHIHIRO;DOI HIROSHI;FURUTA YUKI;KOBAYASHI KAZUKIYO

分类号：C07H3/04;A61K31/785;A61P39/02;C07H15/04;C07H23/00;(IPC1-7):C07H3/04

主分类号：C07H3/04

摘要：PROBLEM TO BE SOLVED: To provide a ligand that can trap the Vero toxin by changing the chemical structure of inexpensive trehalose. SOLUTION: Trehalose, a disaccharide from tow glucoses, is used as a starting substance and the hydroxy group in the 4-position in one glucose is inverted to the axial conformation to introduce the galactose structure whereby the galacto type trehalose or a derivative thereof is produced. The resultant galacto type trehalose or a derivative thereof is introduced into the main chain of a polymer to give the ligand for the Vero toxin.