Derivado de fenilpiperazinil, composto, composição farmacêutica, uso do mesmo, método de tratamento

申请公布号：BR0016951(A)

申请号：BR20000016951

申请日期：2000.12.20

申请公布日期：2003.02.25

申请人：

H. LUNDBECK A/S

发明人：THOMAS RUHLAND;BENNY BANG-ANDERSEN;KIM ANDERSEN;MARIO ROTTLANDER;JAN KEHLER

分类号：C07D413/12;A61K31/496;A61K31/5377;A61K31/551;A61P25/18;A61P25/22;A61P25/24;A61P25/28;C07D209/14;C07D403/06;C07D403/12;C07D405/12;C07D405/14;C07D413/14;(IPC1-7):C07D403/02;C07D403/14;A61K31/537;A61K31/55

主分类号：C07D413/12

摘要："DERIVADOS DE FENILPIPERAZINILA, COMPOSTO, COMPOSIçãO FARMACêUTICA, USO DO MESMO, MéTODO DE TRATAMENTO". A presente invenção refere-se a uma classe inovadora de derivados de fenilpiperazinil tendo a fórmula (i) onde X, Z, Y, U, V, Alqui, W, R^ 1^, R^ 2^, R^ 11^, R^ 12^, n. m e a linha pontilhada são como definidas na descrição. Os compostos da invenção são ligandos receptores de Dopamina D4 e são desta forma úteis para o tratamento de determinados distúrbios psiquiátricos e neurológicos, incluindo psicoses.

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