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USE OF MATRIX METALLOPROTEINASE INHIBITORS TO MITIGATE NERVE DAMAGE

申请公布号:WO2003006006(A1)

申请号:US2002021685

申请日期:2002.07.09

申请公布日期:2003.01.23

摘要:<p>This invention pertains to the discovery that inhibitors of matrix metalloproteinases (e.g. MMP-9) can reduce neurological damage (e.g. secondary damage) following trauma to nervous tissue in a mammal, and/or reduce abnormal vascular permeability associated with spinal cord injury, and/or improving recovery of neurological function following injury to neurological tissue. Methods of use of matrix metalloproteinase inhibitors for such applications are provided.</p>

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