PROCESS FOR PREPARATION OF 2-OXOCARBOXYLIC ACID ESTERS,申请号JP2002006098-传众专利搜索

PROCESS FOR PREPARATION OF 2-OXOCARBOXYLIC ACID ESTERS

申请公布号：WO2003000638(P1)

申请号：JP2002006098

申请日期：2002.06.19

申请公布日期：2003.01.03

摘要：<p>A process for the preparation of 2-oxocarboxylic acid esters represented by the general formula (I), characterized by oxidizing a 2-hydroxycarboxylic acid ester represented by the general formula (II) in the presence of a nitroxyl free radical represented by the general formula (II), a hypochlorite, a metal bromide, and water with the pH of the reaction system being kept within the range of 5 to 7: (II) (III) (I) wherein R1 and R2 are each optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted aryl, or optionally substituted aralkyl; and R3 is hydrogen, alkoxyl, aralkyloxy, acyloxy, or hydroxyl.</p>