夸噻平颗粒
申请公布号:CN1374867A
申请号:CN00813166.X
申请日期:2000.09.18
申请公布日期:2002.10.16
发明人:D·B·布朗
分类号:A61K31/55;A61K9/16;A61K9/00
主分类号:A61K31/55
代理人:王景朝;马崇德
地址:瑞典南泰利耶
摘要:本发明描述了夸噻平和其药学上可接受的盐的颗粒剂、其制备方法及其在治疗中枢神经系统疾病例如精神病包括精神分裂症中的用途。
主权项:1、一种含有11-[4-[2-(2-羟基乙氧基)乙基]-1-哌嗪基]二苯并[b,f][1,4]硫氮杂或其在药学上可接受的盐和任意或极易溶于水的粘合剂的颗粒剂,其中颗粒的松密度在0.15g/cc到0.60g/cc之间,振实密度在0.20g/cc到0.70g/cc之间,且80%的颗粒粒径在75到850微米之间。
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