CYANOPYRROLIDINE DERIVATIVE AND ITS USE FOR MEDICINE

申请公布号：JP2002265439(A)

申请号：JP20010065210

申请日期：2001.03.08

申请公布日期：2002.09.18

申请人：

MITSUBISHI PHARMA CORP

发明人：KITAJIMA HIROSHI;YOSHIDA TOMOHIRO;SONDA SHUJI;AKABOSHI FUMIHIKO;HAYASHI YOSHIHARU

分类号：C07D401/12;A61K31/40;A61K31/4427;A61K31/4439;A61P1/02;A61P3/04;A61P3/10;A61P13/08;A61P17/00;A61P31/18;A61P35/04;A61P37/02;A61P43/00;C07D207/16;(IPC1-7):C07D207/16;A61K31/443

主分类号：C07D401/12

摘要：PROBLEM TO BE SOLVED: To obtain a compound which has a therapeutic effect by DPP-IV inhibitory action and is satisfactory as a medicine. SOLUTION: This cyanopyrrolidine derivative containing a hydrophilic amino group introduced into a side chain is represented by formula (I) (each sign is described in the specification) and has strong DPP-IV inhibitory action and increased stability.

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