Quinoline and quinazoline compounds useful in therapy particularly in the treatment of benign prostatic hyperplasia,申请号OA19999900152-传众专利搜索

Quinoline and quinazoline compounds useful in therapy particularly in the treatment of benign prostatic hyperplasia

申请公布号：OA11074(A)

申请号：OA19999900152

申请日期：1999.07.08

申请公布日期：2002.03.13

申请人：

PFIZER INC.

发明人：DAVID NATHAN ABRAHAM FOX

分类号：A61K31/47;A61K31/4725;A61K31/505;A61K31/517;A61K31/519;A61P13/08;C07D401/04;C07D401/14;C07D405/04;C07D409/04;C07D413/04;C07D471/04;(IPC1-7):C07D409/04;C07D413:04

主分类号：A61K31/47

摘要：<p>Compounds of formula I,whereinR1 represents C1-4 alkoxy optionally substituted by one or more fluorine atoms;R2 represents H or C1-4 alkoxy optionally substituted by one or more fluorine atoms;R3 represents a 5- or 6-membered heterocyclic ring, the ring being optionally substituted;R4 represents a 4-, 5-, 6-, or 7-membered heterocyclic ring, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring, the ring system as a whole being optionally substituted;X represents CH or N; andL is absent, or represents a cyclic group of formula Ia, or represents a chain of formula Ib,and pharmaceutically acceptable salts thereof; are useful in therapy, in particular in the treatment of benign prostatic hyperplasia.</p>