Method and apparatus for analysis of chromatographic migration patterns,申请号US19970933211-传众专利搜索

Method and apparatus for analysis of chromatographic migration patterns

申请公布号：US6208941(B1)

申请号：US19970933211

申请日期：1997.09.16

申请公布日期：2001.03.27

申请人：

UNIVERSITY OF UTAH RESEARCH FOUNDATION

发明人：MARKS ANDREW F.

分类号：G01N33/50;C12M1/00;C12N15/00;C12Q1/68;C12Q1/70;G01N15/06;G01N27/447;(IPC1-7):C12Q1/70

主分类号：G01N33/50

摘要：The present invention includes a method and apparatus for the detection and analysis of information-containing signals in chromatographic data using iterative blind deconvolution and fuzzy logic algorithms. The invented method analyzes chromatographic data from a wide variety of sources of DNA sequencing information, including gel and capillary electrophoresis. Autoradiograms, single-fluor, four-lane and four fluor, single lane fluorescent chromatographic data are suitable sources of unprocessed input data. The output from the invented base calling method includes called (identified) sequence data and quality values for the called bases.