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HUMAN TUMOR NECROSIS FACTOR RECEPTOR TR10
申请公布号：WO0073321(A1)
申请号：WO2000US14554
申请日期：2000.05.26
申请公布日期：2000.12.07
发明人：ROSEN, CRAIG, A.;NI, JIAN
分类号：C12N15/09;A61K38/00;A61K38/17;A61K39/395;A61K45/00;A61K48/00;A61P1/14;A61P1/18;A61P9/10;A61P25/00;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P37/00;C07K14/705;C07K14/715;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02;C12R1/19;C12R1/91;(IPC1-7):C07H21/04;C12P21/06
主分类号：C12N15/09
摘要：The present invention relates to a novel protein, TR10, which is a member of the tumor necrosis factor (TNF) receptor superfamily and the TRAIL receptor subfamily. In particular, isolated nucleic acid molecules are provided encoding the human TR10 protein. TR10 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TR10 activity.
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