METHOD AND APPARATUS FOR INACTIVATION OF BIOLOGICAL CONTAMINANTS USING PHOTOSENSITIZERS,申请号WO1999US16404-传众专利搜索

METHOD AND APPARATUS FOR INACTIVATION OF BIOLOGICAL CONTAMINANTS USING PHOTOSENSITIZERS

申请公布号：WO0004930(A2)

申请号：WO1999US16404

申请日期：1999.07.21

申请公布日期：2000.02.03

申请人：

COBE LABORATORIES, INC.

发明人：GOODRICH, RAYMOND, PAUL, JR.;CORBIN, FRANK, III;WOOD, EDWARD, C., JR.;HLAVINKA, DENNIS

分类号：A61L2/02;A61K35/14;A61L;A61L2/00;A61L2/08;A61L2/10;A61L2/16;A61L2/23;A61M1/36;(IPC1-7):A61L2/00

主分类号：A61L2/02

摘要：Methods and apparatuses are provided for inactivation of microorganisms in fluids or on surfaces. Preferably the fluids contain blood or blood products and comprise biologically active proteins. Preferred methods include the steps of adding an effective, non-toxic amount of an endogenous photosensitizer to a fluid and exposing the fluid to photoradiation sufficient to activate the endogenous photosensitizer whereby microorganisms are inactivated. Other fluids, including juices, water and the like, may also be decontaminated by these methods as may surfaces of foods, animal carcasses, wounds, food preparation surfaces and bathing and washing vessel surfaces. Alloxazines and K- and L- vitamins are among the preferred photosensitizers. Systems and apparatuses for flow-through and batch processes are also provided for decontamination of such fluids using photosensitizers.