Oral contraceptive,申请号AU19970038076-传众专利搜索

Oral contraceptive

申请公布号：AU713016(B2)

申请号：AU19970038076

申请日期：1997.07.23

申请公布日期：1999.11.18

申请人：

AMERICAN HOME PRODUCTS CORPORATION

发明人：MICHAEL JAY GAST

分类号：A61K31/565;A61K31/57;A61K31/58;A61P15/18;(IPC1-7):A61K31/57

主分类号：A61K31/565

摘要：<p>This invention provides a method of contraception which comprises administering to a female of child bearing age for 23-25 consecutive days, a first phase combination of a progestin at a daily dosage of 40-500 mu g trimegestone, 250 mu g - 4mg dienogest, or 250 mu g - 4mg drospirenone, and an estrogen at a daily dosage equivalent in estrogenic activity to 10-20 mu g ethinyl estradiol for 3-8 days beginning on day 1 of the menstrual cycle, wherein the same dosage of the progestin and estrogen combination is administered in each of the 3-8 days, a second phase combination of a progestin at a daily dosage of 40-500 mu g trimegestone, 250 mu g - 4 mg dienogest, or 250 mu g - 4 mg drospirenone, and an estrogen at a daily dosage equivalent in estrogenic activity to 10-20 mu g ethinyl estradiol, for 4-15 days, beginning on the day immediately following the last day of administration of the first phase combination, wherein the same dosage of the progestin and estrogen combination is administered in each of the 4-15 days, and a third phase combination of a progestin at a daily dosage of 40-500 mu g trimegestone, 250 mu g - 4 mg dienogest, or 250 mu g - 4 mg drospirenone, and an estrogen at a daily dosage equivalent in estrogenic activity to 10-20 mu g ethinyl estradiol, for 4-15 days beginning on the day immediately following the last day of administration of the second phase combination, wherein the same dosage of the progestin and estrogen combination is administered in each of the 4-15 days provided that the daily dosage of the combination administered in the first phase is not the same as the daily dosage of the combination administered in the second phase and that the daily dosage of the combination administered in the second phase is not the same as the daily dosage of the combination administered in the third phase.</p>