Anti-LAM 1-3 antibody and hybridoma,申请号US19940215366-传众专利搜索

Anti-LAM 1-3 antibody and hybridoma

申请公布号：US5776775(A)

申请号：US19940215366

申请日期：1994.03.21

申请公布日期：1998.07.07

申请人：

DANA-FARBER CANCER INSTITUTE

发明人：TEDDER, THOMAS F.;SPERTINI, OLIVIER G.

分类号：A61K38/00;C07K14/705;C07K16/28;(IPC1-7):C07K16/18;C12N5/12

主分类号：A61K38/00

摘要：A hybridoma cell line produced by the fusion of NS-1 myeloma cells with spleen cells obtained from mice immunized with Leukocyte Adhesion Molecule-1 (LAM-1) cDNA transfected cells. The cell line produces a monoclonal antibody reactive with human, monkey, cow, rabbit, sheep, dog, cat, pig and goat LAM-1. The monoclonal antibody produced by the cell line, anti-LAMl-3, may be clinically useful in blocking leukocyte entry into sites of inflammation or tissue injury.