Acridinium compound having a plurality of luminescent groups and binding groups, and conjugate thereof,申请号EP19960112276-传众专利搜索

Acridinium compound having a plurality of luminescent groups and binding groups, and conjugate thereof

申请公布号：EP0761652(A1)

申请号：EP19960112276

申请日期：1996.07.30

申请公布日期：1997.03.12

申请人：

MOCHIDA PHARMACEUTICAL CO., LTD.

发明人：SATO, NAOFUMI

分类号：C07D219/04;C07D413/12;C09K11/07;G01N33/533;(IPC1-7):C07D219/04;G01N33/532

主分类号：C07D219/04

摘要：<p>Acridinium compounds and their conjugates exhibiting high chemiluminescence yield are provided. Such compounds may be used to enable a highly sensitive specific binding assay. The acridinium compounds are represented by formula (I): <CHEM> wherein A is a linker; Z is a binding group; Y is a counter ion; R<1> and R<2> are independently a substituent; p and m are independently an integer of from 0 to 4; n is an integer of from 2 to 5; and X is an organic intervening moiety with a functionality of at least n, having an aryloxy group or an arylsulfonamide group through which X binds to carbonyl carbon bonded to 9-position of the acridinium ring. <IMAGE></p>