Pyrimidine deoxyribonucleoside potentiation of combination therapy based on 5-fluorouracil and interferon

申请公布号：US5496810(A)

申请号：US19940226499

申请日期：1994.04.12

申请公布日期：1996.03.05

申请人：

MONTEFIORE MEDICAL CENTER

发明人：SCHWARTZ, EDWARD L.

分类号：A61K38/21;(IPC1-7):A61K31/505;A61K31/70

主分类号：A61K38/21

摘要：The applicants have discovered a method of treating malignancies which comprises administering effective amounts of 5-fluorouracil, interferon- alpha and a compound formula (I): <IMAGE> (I) wherein R is selected is selected from the group consisting of alkyl of 1 to 5 carbon atoms, alkene of 2 to 5 carbon atoms and alkynyl of 2 to 5 carbon atoms; R1 is 2'-deoxyribofuranosyl.

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