Ionic reservoir at electrode surface,申请号AU19920014657-传众专利搜索

Ionic reservoir at electrode surface

申请公布号：AU666113(B2)

申请号：AU19920014657

申请日期：1992.03.27

申请公布日期：1996.02.01

申请人：

AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE

发明人：LIONEL GEORGE KING;BURKHARD RAGUSE;BRUCE ANDREW CORNELL;RONALD JOHN PACE

分类号：A61B5/0408;C07C323/12;C07D495/04;C07J31/00;C07K7/08;C12Q1/00;G01N27/333;G01N27/40;G01N33/543

主分类号：A61B5/0408

摘要：PCT No. PCT/AU92/00132 Sec. 371 Date Sep. 21, 1993 Sec. 102(e) Date Sep. 21, 1993 PCT Filed Mar. 27, 1992 PCT Pub. No. WO92/17788 PCT Pub. Date Oct. 15, 1992.The present invention relates to electrode membrane combinations for use in biosensors. The membrane is attached to the electrode by means of a linker molecule in a manner such that a hydrophilic space is provided between the membrane and the electrode. The linker molecule comprises within the same molecule a hydrophobic region which constitutes at least a proportion of the amphiphilic molecules making up the membrane or is attached to or is embedded in the membrane, an attachment region attached to the electrode and a hydrophilic region intermediate said hydrophobic and attachment regions. The hydrophilic region spans the space between the membrane and the electrode.