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Modified thioredoxin and its use

申请公布号:SE468480(B)

申请号:SE19910001586

申请日期:1991.05.24

申请公布日期:1993.01.25

申请人:
ARNE HOLMGREN;GUNTER KRAUSE;JOHANNA LUNDSTROEM

发明人:ARNE HOLMGREN;GUNTER KRAUSE;JOHANNA LUNDSTROEM

分类号:C12N9/02

主分类号:C12N9/02

摘要:Thioredoxin comprising a redox-active Cys32-X-Pro34-Cys35 site (E.coli numbering) or a functional derivative thereof in which the amino residue Pro in position 34 has been replaced with His and in which the amino acid residue X in position 33 is selected from Gly and Ala; processes for preparing folded biologically active disulphide-crosslinked proteins in vitro using such thioredoxin; and these processes carried out in the presence of a catalytic quantity of a selenite.

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