PROCESS FOR PRODUCING THIOALKYL THIOCAFALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS AS ACTIVE INGREDIENT,申请号HU19910002409-传众专利搜索

PROCESS FOR PRODUCING THIOALKYL THIOCAFALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS AS ACTIVE INGREDIENT

申请公布号：HUT60274(A)

申请号：HU19910002409

申请日期：1991.07.18

申请公布日期：1992.08.28

申请人：

SHIONOGI AND CO. LTD.,JP

发明人：KUBOTA,TADATOSHI,JP;KUME,MASAHARU,JP

分类号：A61K31/545;A61K31/546;A61P31/00;A61P31/04;C07D249/04;C07D249/08;C07D401/06;C07D501/00;C07D501/04;C07D501/06;C07D501/59;(IPC1-7):C07D501/46

主分类号：A61K31/545

摘要：<p>A novel thioalkylthio cephalosporin antibiotic compound of formula I: <CHEM> wherein Acyl is C1 - C12 acyl; Het is optionally substituted monocyclic heteroaromatic group containing one or more hetero atoms; R<1> is a single bond or C1 - C4 alkylene; R2 is a straight or branched C1 - C4 alkylene; X is a sulfur atom or sulfoxide group; and Y is a hydrogen atom or methoxy group, or a pharmaceutically acceptable salt or an amino-, carboxy- and/or hydroxy-protected derivative thereof, a formulation containing the same and a method for treating bacterial infections.</p>