Direct delivery of anti-inflammatories to the proximal small bowel,申请号US19900496667-传众专利搜索

Direct delivery of anti-inflammatories to the proximal small bowel

申请公布号：US5120306(A)

申请号：US19900496667

申请日期：1990.03.21

申请公布日期：1992.06.09

申请人：

GOSSELIN, LEON F.

发明人：GOSSELIN, LEON F.

分类号：A61J15/00

主分类号：A61J15/00

摘要：Transpyloric treatment of small bowel inflammation (e.g. Crohn's disease) by topical application of anti-inflammatory agents such as 5-ASA, 4-ASA or 3-ASA has hitherto been by oral administration of tablets the accurate targeting of which, in the variable environment of the gut, has been impossible. Now, by using an enteric feeding tube, an effective amount of an agent like 5-ASA may be delivered directly to the inflamed segment fo the gastrointestinal tract in patients suffering from inflammatory bowel disease whereby the agent is brough into direct, topical contact with inflamed mucosa while avoiding prior degradation in the stomach.