Method and apparatus for pulsed iontophoretic drug delivery

申请公布号：US5047007(A)

申请号：US19890456013

申请日期：1989.12.22

申请公布日期：1991.09.10

申请人：

MEDTRONIC, INC.

发明人：MCNICHOLS, LARRY A.;LATTIN, GARY A.

分类号：A61N1/30;A61N1/32

主分类号：A61N1/30

摘要：A method and apparatus are disclose for transdermal iontophoretic delivery of ionic species, such as a drug in ionic form, in which therapeutic, electrical pulses having controlled, distinctive, dual-segment waveform characteristics are applied which facilitate more efficient drug administration throughout each pulse. The therapeutic pulses are generated at a predetermined frequency and have a predetermined pulse width. A first pulse segment and a second pulse segment comprise each dual-segment, therapeutic pulse. The electrical attributes of each pulse segment, including amplitude and duration, are controlled to produce the desired, pulsed output waveform.

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