Polysubstituted 2-morpholones, related compounds, processes for their preparation, and U-V light stabilized compositions,申请号US19870101523-传众专利搜索

Polysubstituted 2-morpholones, related compounds, processes for their preparation, and U-V light stabilized compositions

申请公布号：US4914232(A)

申请号：US19870101523

申请日期：1987.09.28

申请公布日期：1990.04.03

申请人：

THE B. F. GOODRICH COMPANY

发明人：LAI, JOHN TA-YUAN

分类号：C07D265/32;C07D265/34;C07D273/00;C07D295/02;C07D295/023;C07D295/027

主分类号：C07D265/32

摘要：An essentially single stage reaction has been discovered in which a disubstituted ethanolamine, that is, a 2,2'-substituted-2-aminoethanol, may be reacted with a haloform and a carbonyl containing compound selected from the group consisting of monoketones and benzaldehyde, in the presence of an alkali metal hydroxide, and optionally in the presence of a phase transfer catalyst, to produce an alkali metal hydroxyethylaminoacetate ("HEAA") which has N-adjacent C atoms on which there are a total of at least three substituents (hence "polysubstituted"), and one or both pairs of substituents on each N-adjacent C atom may be cyclized. The HEAA may be cyclized by the action of a mineral acid to produce a 2-morpholone hydrochloride which is characterized by having a total of at least three substituents on the N-adjacent C atoms of the ring. The 2-morpholone so produced may be reduced to a polysubstituted aminodiol. The aminodiol so produced may be cyclized with an alkane sulfonic acid to yield a polysubstituted morpholine which could not otherwise have been made. The aminodiol may also be alkylated to produce diethers with polysubstituted N-adjacent C atoms. If the aminodiol is tosylated, a polysubstituted crown ether is produced with plural polyalkylene groups. The foregoing HEAA and related compounds are used as u-v light stabilizers in novel compositions in which a small but effective amount of one or more of the HEAA and related compounds is incorporated, in an amount sufficient to produce desirable stabilization against degradation by u-v light in a wide variety of organic materials.