CANCER DETECTION PREPARATIONS AND METHOD,申请号US1988002099-传众专利搜索

CANCER DETECTION PREPARATIONS AND METHOD

申请公布号：WO1989012466(A1)

申请号：US1988002099

申请日期：1988.06.20

申请公布日期：1989.12.28

摘要：<p>A method for detecting cancer comprises intradermally injecting into a patient a test preparation comprising a glycoprotein-polysaccharide-like antigenic substance admixed with the patient's blood serum. The patient's serum is also injected intradermally as a control and the physical dimensions of the erythemas of the injections measured and compared as an indication of the presence of cancer. An initial antigenic substance is derived from cancerous tissues by disintegrating the tissue to enable the separation of the nuclei and cell membranes from the mitochondrial fraction of the cell. After lipids are removed from the mitochondrial fraction, it is hydrolyzed in hot alkali, dialyzed and then deproteinated. The cancer specificity of the antigenic substance is enhanced by gel filtration. Prior to admixture with the antigenic substance, the blood serum is subjected to an adsorptive procedure to remove non-cancerous antibodies which might otherwise be reactive with the antigenic substance. A proteolytic enzyme (e.g trypsin) is added to a portion of the blood serum: to provide, in the preferred embodiment, additional cancer detection preparations.</p>