N-(2,6-DISUBSTITUTED AROMATIC)-N'-PYRIDINYL UREAS, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME,申请号DE19843480391-传众专利搜索

N-(2,6-DISUBSTITUTED AROMATIC)-N'-PYRIDINYL UREAS, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME

申请公布号：DE3480391(D1)

申请号：DE19843480391

申请日期：1984.08.06

申请公布日期：1989.12.14

申请人：

WARNER-LAMBERT COMPANY

发明人：LOBBESTAEL, SANDRA J.;NORDIN, IVAN C.;FLEMING, ROBERT

分类号：A61K31/44;A61K31/4406;A61K31/4409;A61P25/08;C07D213/75;(IPC1-7):C07D213/75

主分类号：A61K31/44

摘要：N-2,6-Disubstituted phenyl(-N min -3- and 4-pyridinyl ureas having the following general formula are disclosed: <CHEM> A is a 3- or 4-pyridinyl radical; and R<1>, R<2> and R<3> are independently chosen from a halogen atom, a lower alkyl radical, a lower alkoxy radical, a lower alkanoyl radical, a lower alkoxy carbonyl radical or a nitro group. with R<3> additionally being chosen from a hydrogen atom. Processes for producing the compounds, pharmaceutical compositions comprising the same, and pharmaceutically acceptable acid addition salts thereof are also disclosed. The compounds have anti-convulsant activity and are useful in the treatment of epilepsy.