POLYPEPTIDES WITH FIBRONECTIN ACTIVITY,申请号AU19880023859-传众专利搜索

POLYPEPTIDES WITH FIBRONECTIN ACTIVITY

申请公布号：AU2385988(A)

申请号：AU19880023859

申请日期：1988.08.24

申请公布日期：1989.03.31

申请人：

REGENTS OF THE UNIVERSITY OF MINNESOTA

发明人：LEO T. FURCHT;JAMES B. MCCARTHY

分类号：A61L15/16;A61F2/06;A61F2/16;A61F2/24;A61F2/32;A61K38/00;A61L27/00;A61L27/22;A61L27/28;A61P43/00;C07K7/06;C07K7/08;C07K14/47;C07K14/78;C12N5/00

主分类号：A61L15/16

摘要：A polypeptide which can bind heparin and promote cellular adhesion and neurite outgrowth is provided of the formula: lys-asn-asn-gln-lys-ser-glu-pro-leu-ile-gly-arg-lys-lys-thr, leu-ile-gly-arg-lys-lys-thr, tyr-arg-val-arg-val-thr-pro-lys-glu-lys-thr-gly-pro-met-lys-glu, ser-pro-pro-arg-arg-ala-arg-val-thr, trp-gly-pro-pro-arg-ala-arg-ile, or mixtures thereof. Medical devices such as prosthetic implants, percutaneous devices and cell culture substrates coated with the polypeptide composition are also provided.