IMMOBILISERADE VIA SITT MODIFIERADE KOLHYDRATOMRAADE KOVALENT TILL EN MATRISPOLYMER BUNDNA ANTIKROPPAR,申请号SE19880004100-传众专利搜索

IMMOBILISERADE VIA SITT MODIFIERADE KOLHYDRATOMRAADE KOVALENT TILL EN MATRISPOLYMER BUNDNA ANTIKROPPAR

申请公布号：SE8804100(L)

申请号：SE19880004100

申请日期：1988.11.14

申请公布日期：1988.11.14

申请人：

ROEHM GMBH

发明人：SOLOMON B

分类号：A61K39/44;C07K16/00;C07K17/06;C07K17/08;C12P21/08;G01N33/543;G01N33/545;G01N33/547;G01N33/548

主分类号：A61K39/44

摘要：Antibodies which are immobilized and covalently bound to a matrix polymer by means of a modification in a carbohydrate region of the antibodies; wherein the binding of the antibodies is effected by condensing at least one aldehyde group in an oxidized carbohydrate region and at least one epoxide function of an epoxy-group-containing matrix polymer, said condensation being conducted in the presence of a bifunctional reagent which has, on one end position of a spacer unit having at least three members, an amino group capable of condensing with the aldehyde group, and which has on the other end position a group which reacts covalently with the epoxide function.