SETT ATT FRAMSTELLA ETT KONCENTRAT AV PROTROMBINKOMPLEX,申请号SE19800009157-传众专利搜索

SETT ATT FRAMSTELLA ETT KONCENTRAT AV PROTROMBINKOMPLEX

申请公布号：SE452250(B)

申请号：SE19800009157

申请日期：1980.12.29

申请公布日期：1987.11.23

申请人：

INSTITUT MERIEUX

发明人：1)M * CHANAS;2)J * LIAUTAUD;3)E * SHANBROM

分类号：C07K14/745;A61K38/00;C07K14/00;C07K14/435;C12N9/74;(IPC1-7):A61K35/16;C07K15/06

主分类号：C07K14/745

摘要：Procedure for the preparation of a concentrate of prothrombinogenic compound. This procedure, in which, starting from a source of prothrombinogenic compound, an adsorption is followed by an elution, is characterized by the fact that a source of prothrombinogenic compound and a source of antithrombin III (or AT III) is placed in contact with an adsorbing agent capable of adsorbing both the prothrombinogenic compound and antithrombin III, and that the foregoing occurs in the presence of heparin, at least during the elution stage, and that elution is carried out with an elution agent capable of eluting the prothrombinogenic compound, the AT III and heparin at the same time. Application of the product obtained, notably to the treatment of blood coagulation difficulties.