REPLIKERANDE EXPRESSIONSVEKTOR, FOERFARANDE FOER DESS FRAMSTAELLNING SAMT DESS ANVAENDNING VID FRAMSTAELLNING AV HUMAN LEUKOCYTINTERFERON.

申请公布号：FI863001(A)

申请号：FI19860003001

申请日期：1986.07.21

申请公布日期：1986.07.21

申请人：

F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT;GENENTECH, INC.

发明人：GOEDDEL, DAVID VAN NORMAN;PESTKA, SIDNEY

分类号：C12N;C12N1/21;C12N15/21;C12N15/63;C12N15/70;(IPC1-7):C12N/

主分类号：C12N

摘要：The invention relates to a replicating expression vector, which is able to express human leukocyte interferon in a microorganism which is transformed with this replicating expression vector, and which comprises a first DNA sequence which encodes mature leukocyte interferon, with this DNA sequence being functionally linked to a second DNA sequence which brings about microbial interferon expression. The invention furthermore relates to a process for preparing this expression data and to the use of the expression vector for preparing mature leukocyte interferon.

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