Antibiotic A 40926 complex and its pure factors PA, PB, A, B and BO.,申请号EP19850112406-传众专利搜索

Antibiotic A 40926 complex and its pure factors PA, PB, A, B and BO.

申请公布号：EP0177882(A2)

申请号：EP19850112406

申请日期：1985.10.01

申请公布日期：1986.04.16

申请人：

GRUPPO LEPETIT S.P.A.

发明人：SELVA, ENRICO;GASTALDO, LUCIANO;BERETTA, GRAZIA;BORGHI, ANGELO;GOLDSTEIN, BETH P.;ARIOLO, VITTORIO;CASSANI, GIOVANNI;PARENTI, FRANCESCO

分类号：A61K35/74;A61K38/00;A61P31/04;C07G11/00;C07K9/00;C12N1/20;C12P1/06;C12R1/03;(IPC1-7):C07G11/00;A61K35/70;C07K15/02

主分类号：A61K35/74

摘要：<p>The present invention concerns a new antibiotic substance arbitrarily denominated antibiotic A 40926 complex and its factors antibiotic A 40926 factor A antibiotic A 40926 factor B. antibiotic A 40926 factor B<Sub>o</Sub>, antibiotic A 40926 factor PA and antibiotic A 40926 factor PB, a process for producing them by culturing the new strain Actinomadura sp. ATCC 39727 or an A 40926 producing variant or mutant thereof and the use of these new antibiotic substances in the treatment of infectious diseases involving microorganisms susceptible to them. The antibiotic substances of the invention are glycopeptidic substances belonging to the vancomycin class or antibiotics which have binding capacity to Acyl-D-Alanyl-D-Alanine.</p>